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Participant payments built for UK clinical trial compliance

vHelp is a UK-based payment platform that pays stipends and reimburses expenses directly to participants' bank accounts within 24 hours. GDPR-native, MHRA audit-ready, and fully aligned with April 2026 UK clinical trial regulations from day one.

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Looking to reimburse volunteers instead? see vHelp for Volunteers

Paying participants via BACS or prepaid cards is costing you time, money and retention

Fees, delays and failed activation

Prepaid cards are challenging to activate and carry fees for the participant. BACS batch runs mean weeks of waiting after a visit. Both kill retention.

GDPR risk

Prepaid card providers, typically US-based, require KYC data from participants, ie. passports and date of birth, stored outside UK jurisdiction. With BACS, bank details are shared across spreadsheets and inboxes. The ICO holds you accountable.

No expenses audit trail

BACS processes rely on spreadsheets and manual records, there is no single source of truth. With prepaid cards, funds dispensed by your organisation may never reach the participant. You cannot prove what was actually paid

April 2026 UK clinical trial regulations, are you ready?

The Medicines for Human Use Clinical Trials Regulations 2025 come into force on 28 April 2026, the most significant reform of UK clinical trial regulation in over two decades. Sites, sponsors and CROs must demonstrate robust, auditable payment processes. vHelp is fully aligned from day one, no retrofitting required

From visit to bank account in three steps

Participants or site team log an expense and stipend in seconds. Site staff approve in one click. Funds land within 24 hours, with a full audit trail at every stage, inspection ready from day one.

Participant or site team logs a claim

The participant or a site coordinator logs an expense or stipend through the vHelp app or website. Takes under a minute on any device

Site coordinator approves

Review the claim and approve it in one click. Multi-level approval supported for CROs managing multiple sites. Actions timestamped and logged for audit.

Funds land in 24 hours

Expenses and stipends are reimbursed directly to the participant's bank account within 24 hours of final approval.

Direct to bank in 24 hours

Participants receive stipends and expense reimbursements directly into their bank account within 24 hours of final approval. Fast, traceable, and 100% of funds reach the participant.

MHRA-ready audit trail

Centralised dashboard, digital receipts and automated reporting. Download a complete payment report in seconds, CSV or PDF, with receipt photos presented as a direct link in the exported report. Ready for sponsors, and regulators

UK data sovereignty

All participant data stored within the UK. GDPR-native by design, not bolted on. We capture only the data needed to process the payment, reducing KYC risk from the ground up. ICO registered. No compliance gaps.

Simple participant experience

Direct to bank means no card activation headaches, no fees eating into their payment, no waiting and no intrusive data capture. Participants receive 100% of the funds disbursed to them.

 

Multi-site management

Sites can  manage participant expenses and first-level approvals independently. A second centralised approval can be enabled before payment is released. 

April 2026 compliant

Fully aligned with the Medicines for Human Use Clinical Trials Regulations 2025, effective 28 April 2026. No extra work needed on your end. vHelp is regulation-ready from day one.

85%
Reduction in expense admin
24hrs
To reimbursement
100%
Of funds reach users' account
100%
GDPR Compliant

TRUSTED BY

Clinical trial reimbursement: frequently asked questions

How should CROs pay clinical trial participants in the UK?

UK CROs and trial sites should pay participants directly to their bank account using a compliant, auditable platform. Direct bank payment eliminates prepaid card fees, creates a clear audit trail, and ensures UK data sovereignty. vHelp processes participant stipends and expense reimbursements directly to bank within 24 hours, with every transaction timestamped and exportable for regulatory review. See how it works

What are the April 2026 UK clinical trial payment regulations?

The Medicines for Human Use Clinical Trials Regulations 2025 come into force on 28 April 2026, representing the most significant reform of UK clinical trial regulation in over two decades. The regulations place greater emphasis on participant welfare, transparent reimbursement processes and auditable payment records. Sites, sponsors and CROs must demonstrate that payment processes are robust, compliant with UK GDPR and fully documented. vHelp is aligned with these requirements from day one, no retrofitting required Read the official guidelines here

Is BACS compliant for clinical trial participant payments?
BACS itself is not inherently non-compliant, but the typical BACS process (monthly batch runs, manual spreadsheet management, no real-time audit trail) creates significant compliance risk. The lack of per-transaction audit records, the delay to payment and the manual data handling all introduce risk that regulators are increasingly scrutinising. vHelp replaces the BACS batch process with direct, per-transaction bank payments that are faster, fully auditable and GDPR-native.
What counts as a reimbursable expense and what is a stipend in a UK clinical trial?

A reimbursable expense covers a specific, documented out-of-pocket cost a participant incurs attending a trial visit, such as travel, parking, meals or accommodation. Where a receipt is required, the participant provides attached to the expense claim.

A stipend is a fixed payment made for a participant's time and inconvenience at a visit. It is not tied to a specific cost and does not require a receipt. The amount is set by the sponsor and disclosed in the participant information sheet.

Both are common in UK clinical trials. vHelp handles expenses and stipends within the same platform. Participants or site team log both through out workflow, and funds land in the participant's bank account within 24 hours of final approval.

 

How do prepaid cards create a GDPR risk in clinical trials?

Most prepaid card providers used in clinical trials are US-based companies. To activate a card, participants must submit full KYC data, including their full name, date of birth and a copy of their passport. This data is stored outside UK jurisdiction, creating an immediate data sovereignty problem.

As the Data Controller, you cannot outsource your legal accountability under UK GDPR. Any payment processor you use must handle participant data within UK jurisdiction and capture only what is necessary. With prepaid cards, extensive KYC data is collected and stored abroad.

With vHelp, only the minimum data needed to process a payment is captured, and all data stays within the UK.

Can the site team submit expenses on behalf of participants?

Yes. The site team can log an expense or stipend on behalf of any participant in seconds. Participants can also submit their own claims through the vHelp app or dashboard independently.

vHelp is designed to be straightforward for everyone. At Bradford Museums and Galleries, a user in her 70s was showing younger users how to upload receipts and submit their own claims. 

How do I reduce participant payment admin at my trial site?

The biggest drivers of payment admin are manual data entry, paper-based claim forms and monthly batch payment runs. vHelp eliminates all three. Participants or site team submit claims digitally in under a minute. Coordinators approve in one click. Payments process automatically to bank within 24 hours. Organisations using vHelp report an 85% reduction in expense admin time compared to previous manual processes.

 

Ready to simplify participant payments?

Join organisations already using vHelp to pay participants faster, with a full audit trail and zero compliance risk.

Get in touch: hello@vhelp.co.uk